INVESTIGATION: Identification and detection of mutations involved in transcriptional regulation of genes mediating insecticide resistance in the major malaria vector Anopheles funestus.
This study revealed that, Cis-regulatory polymorphisms are driving the overexpression of CYP6P9a and CYP6P9b insecticide resistance genes. Evidence shows that, a major fraction of the global infectious disease burden is due to vector-borne diseases. Malaria being one of such diseases, is the number one killer and, is caused by a protozoan of the Plasmodium genus..…