Category Archives: News

PUBLICATION: “Long-term impact of exposure to Royal Guard, a pyriproxyfen-based bed net, on pyrethroid-resistant malaria vectors from Cameroon using DNA-based metabolic resistance markers” by Sonia Ngongang & al

 Delayed Impact of exposure to Royal Guard on pyrethroid-resistant malaria vectors.  The increasing pyrethroid resistance in malaria vectors underscores the need for control tools using non-pyrethroid molecules. This study assesses the efficacy of Alpha cypermethrin + pyriproxyfen, the dual active ingredient (ai) used in Royal Guard net, focusing on its long-term effects on mosquito life…

Training: CRID researchers provide lectures on Medical Entomology to Master’s students

This was from the 6th-17th January 2025 at the Lambaréné Medical Research Centre (CERMEL) in Gabon  Dr Tchouakui giving a course on Detection and Management of resistance For two weeks, a team of CRID researchers dispensed courses to a cohort of 15 students from different African countries. This was part of a Master’s program in…

PUBLICATION: “Two highly-selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b genes drive pyrethroid resistance in Anopheles funestus in West Africa”, by Nelly Manuela Tchatchoua & al 

Illustration caption: Fig. 3 In vitro assessment of pyrethroid metabolism by CYP6P4a and CYP6P4b candidate alleles. A CYP6P4a recombinant enzyme metabolism of pyrethroids. B CYP6P4b recombinant enzyme metabolism of pyrethroids. Values are mean ± SEM of three experimental replicates compared with negative control without NADPH. Depletion by recombinant resistant enzymes is significantly different from depletion…