Background
He did his PhD on Bioecology and population genetic of Aedes aegypti and Aedes albopictus, two major arbovirus vectors in Cameroon at the University of Yaounde I. After defending his thesis in June 2011, he joined the Pasteur Institute in Bangui in September 2011 for a postdoctoral position. He continued to work and develop my skills by assessing entomological and virological risks for emergence of arboviruses notably chikungunya virus in the Central African Republic. Unfortunately, due to civil war in the CAR, this project was interrupted and I was forced to have a career break of more than a year, the time to adjust to the unexpected situation in Bangui. However, in 2015, he has been working as a consultant on a project of Prof Jeff Powell from the Department of Ecology and Evolutionary Biology (Yale University) on genetic structure of Ae. aegypti in Yaoundé. In the same year he joined the Research Unit of the Liverpool School of Tropical Medicine based at OCEAC lead by Prof Charles Wondji. During this period he was granted by a Wellcome Trust for three years projects. Since January 2018, he is based at Centre for Research in Infectious Diseases as lead of the Medical Entomology Department.
Research:
- Areas of interest:
Arbovirus vectors, vector competence, population genetic, insecticide resistance
- Research – an overview of his research areas(s)
His main interest is to decipher the factors leading to the arboviral diseases outbreaks in Central Africa and prepare the region for intervention in case of outbreaks by analysing in depth the vectorial capacity, molecular bases of insecticide resistance, genetic diversity and population structure of arbovirus vectors. His primary program is focused on understanding the process of invasion of Central Africa by the invasive species Ae. albopictus and its impact on the distribution and prevalence of resident species Ae. aegypti. He is also working on the epidemiological risk of Ae. aegypti and Ae. albopictus to emergence arbovirus outbreaks in Central Africa by detecting the origin of blood meals and arboviruses circulating in field collected mosquitoes. He is defining on the genetic structure and gene flow in Aedes albopictus from Central Africa using microsatellites and mitochondrial DNA genes. He is developing a program on vector competence of Ae. aegypti and Ae. albopictus from central Africa toward dengue, Zika and Yellow fever viruses. He is defining the resistance profile of Ae. aegypti and Ae. albopictus in Central Africa. Currently he is working on the resistance mechanism involved in Aedes using transcriptomic analysis (RNAseq)
He has also the general interest in serological and virological analysis of arboviruses including dengue, chikungunya, Rift Valley Fever and Zika viruses in Central Africa.
- Research Areas:
Arbovirus and Arthropod vectors
- PhD Students:
- Aurelie Yougang, University of Yaounde I, Cameroon
- Theodel Adjete Wilson-Bahun, Marien Ngouabi University, The Republic of the Congo
- Armel Tedjou, University of Yaounde I, Cameroon
Other relevant expertise, professional memberships, etc
- Associate Editor BMC Infectious Diseases and Parasites and Vectors
- Member West African Aedes surveillance network
- Member Pan Africa Mosquito Control Association, Cameroon branch
Publications
1. Yougang AP, Kamgang B, Wilson-Bahun TA, Tedjou NA, Nguiffo-Nguete D, Njiokou F, Wondji CS.2020. First detection of F1534C knockdown resistance mutation in Aedes aegypti (Diptera: Culicidae) from Cameroon. Infect Dis Poverty 9, 152 (2020). https://doi.org/10.1186/s40249-020-00769-1
2. Wilson-Bahun TA, Kamgang B, Lenga A, Wondji CS. 2020. Larval ecology and infestation indices of two major arbovirus vectors, Aedes aegypti and Aedes albopictus (Diptera: Culicidae), in Brazzaville, the capital city of the Republic of the Congo. Parasit Vectors. 2020 Sep 25;13(1):492. doi: 10.1186/s13071-020-04374-x.
3. Tedjou AN*, Kamgang B*, Yougang AP, Wilson-Bahun TA, Njiokou F, Wondji CS. 2020. Patterns of Ecological Adaptation of Aedes aegypti and Aedes albopictus and Stegomyia Indices Highlight the Potential Risk of Arbovirus Transmission in Yaoundé, the Capital City of Cameroon. Pathogens. 2020 Jun 20;9(6):491. doi: 10.3390/pathogens9060491. * equal contribution
4. Yougang AP*, Kamgang B*, Tedjou AN, Wilson-Bahun TA, Njiokou F, Wondji CS. 2020. Nationwide profiling of insecticide resistance in Aedes albopictus (Diptera: Culicidae) in Cameroon. PLoS One. 2020 Jun 18;15(6):e0234572. * equal contribution.
5. Kamgang B, Vazeille M, Tedjou A, Yougang AP, Wilson-Bahun TA, Mousson L, Wondji CS, Failloux AB. Different populations of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) from Central Africa are susceptible to Zika virus infection. PLoS Negl Trop Dis. 2020 Mar 23;14(3):e0008163. doi: 10.1371/journal.pntd.0008163.
