Background
| I am senior researcher since 2017. I hold a PhD and HDR in parasitology and medical entomology from the University of Yaoundé 1 Cameroon and Montpellier 2 France. Although my primary research focus is on malaria vectors, I also work on arbovirus vectors (Dengue, chikungunya, Yellow fever …), Human African Trypanosomiasis and onchocerchiasis. My research encompasses both basic and applied aspects of malaria, focusing on malaria epidemiology, vector bionomic, taxonomy, vector control, population genetic structure, molecular biology and insecticide resistance. I have an established record of productivity in many aspects of malaria, with more than 110 peer-reviewed publications. I believe a better understanding of vector population evolution could be critical for the successful elimination of vector borne diseases. I managed a research team of over 20 people. I have trained over 40 students at master, PhD and postdoctoral level. Throughout my career, I have fostered important international collaborations. I have been for over seven years the training coordinator of the higher school for public health in Central Africa (CIESPAC) and project coordinator at OCEAC. |
Research:
- Areas of interest:
Malaria vector bionomic Vector control (Larviciding, LLINS )
Vector surveillance
Surveillance of arbovirus vectors
Surveillance of human African trypanosomiasis
- Research – an overview of your research areas(s)
| Malaria vector bionomic & control: I have contributed to the characterization of secondary malaria vectors in Central Africa. These studies have permitted to raise awareness on the real contribution of these species to malaria transmission. I also contributed to the development of new molecular tools (microsatellites, cytogenetic map) for genetic studies on An. nili and An. moucheti two important malaria vectors in the forest region. I conducted important studies to assess the impact of deforestation and urbanization on malaria vector bionomic in central Africa. Studies in major cities of Cameroon (Douala and Yaoundé) permitted to report the adaptation of the malaria vectors An. gambiae and An. coluzzii to the urban environment. I also conducted a large scale larviciding trial in the city of Yaoundé providing evidences on the efficacy of this intervention in urban settings.
Insecticide Resistance: I have contributed in the study of insecticide resistance by carrying surveillance activities in various part of Cameroon and by mapping the distribution of resistance mechanisms in malaria vectors. I also wrote a review on the situation of insecticide resistance across Cameroon. These data guided the NMCP in the planning of their activities on the field and the development of strategic documents such as the national plan for insecticide resistance management. Bionomic of Culex mosquitoes: I initiated since 2017 a serie of studies to assess the bionomic of Culex mosquitoes who happen to induce high burden in urban settings and who were up till now not well studied. My studies provided critical information on their biology, resistance to insecticide and epidemiological role in urban settings. The rapid expansion of insecticide resistance in Culex species is now affecting all insecticide classes. I also wrote a review summarizing information on this species distribution in Cameroon since the 1960.
Arbovirus transmission and Aedes bionomic: I have developed several studies intended to understand the transmission of arboviruses in Cameroon and on the bionomic of Aedes species in Cameroon. My studies indicated the circulation of both dengue and chikungunya in the country and the presence of several dengue serotypes circulating in the population. Vector surveillance studies indicated the adaptation of Aedes albopictus and Aedes aegypti to various type of environment and emergence of insecticide resistance in these mosquitoes with new resistance mechanisms appearing. Human African Trypanosomiasis (HAT): I undertook studies on this disease which is target for elimination by 2030 but which is still responsible for a high burden in central Africa. My studies in the Republic of Congo indicated a high circulation of animal trypanosomiasis in endemic foci and the distribution of different tsetse flies species which could be vector of human HAT. We also highlighted the influence of different factors in endemic foci which could influence the epidemiology of this disease. |
- Other Relevent Expertise, PROFESSIONAL MEMBERSHIPS
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President of the Cameroon PAMCA Chapter Board member of PAMCA (Pan African Mosquito Control Association) since 2010
- PhD students
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I have supervised 7 PhD who have defended their thesis at the university of Yaoundé 1 and university of Dschang I am supervisor of 10 PhD students at the university of Yaoundé 1, Dschang and Douala
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Publications
| Some of my recent publications out of 110
Kala-Chouakeu NA, Tchuinkam T, Bamou R, Bindamu MM, Talipouo A, Kopya E, Awono-Ambene P, Antonio-Nkondjio C. Malaria transmission pattern across the sahelian, humid savanna, highland and forest eco-epidemiological settings in Cameroon. 2023. 22:116 https://doi.org/10.1186/s12936-023-04544-z Carmène Sandra Ngadjeu, Abdou Talipouo, Sévilor Kekeunou, Patricia Doumbe-Belisse, Idriss Nasser Ngangue-Siewe, Landre Djamouko-Djonkam, Edmond Kopya, Roland Bamou, Nadège Sonhafouo-Chiana, Leslie Nkahe, Metoh Theresia Njuabe, Parfait Awono-Ambene, Charles Sinclair Wondji, Christophe Antonio-Nkondjio Knowledge, practices and perceptions of communities during a malaria larviciding randomized trial in the city of Yaoundé, Cameroon. PLoS One. 2022; 17(11): e0276500. Published online 2022 Nov 3. doi: 10.1371/journal.pone.0276500 PMCID: PMC9632894 Irina Bemba, Arsene Lenga, Herman Parfait Awono-Ambene, Christophe Antonio-Nkondjio Tsetse Flies Infected with Trypanosomes in Three Active Human African Trypanosomiasis Foci of the Republic of Congo. Pathogens. 2022 Nov; 11(11): 1275. Published online 2022 Oct 31. doi: 10.3390/pathogens11111275 PMCID: PMC9699545 Stella Mariette Nana-Ndjangwo, Borel Djiappi-Tchamen, Ruth Mony, Maurice Demanou, Joyce Keumezeu-Tsafack, Roland Bamou, Parfait Awono-Ambene, Charles Félix Bilong Bilong and Christophe Antonio-Nkondjio. Assessment of dengue and chikungunya infections among febrile patients visiting four healthcare centres in Yaoundé and Dizangué, Cameroon. Viruses, 14, 2127. Nelly Armanda Kala-Chouakeu, Paulette Ndjeunia-Mbiakop, Idriss Nasser Ngangue-Siewe,, Mavridis Konstantinos, Vasileia Balabanidou, Roland Bamou, Maxim Mabu Bindamu, Abdou Talipouo, Landre Djamouko, Jean Arthur Mbida Mbida, Jeanette Tombi, John Vontas, Timoléon Tchuinkam and Christophe Antonio-Nkondjio. Pyrethroid resistance situation across different eco-epidemiological settings in Cameroon. Molecules 27, 6343. Djiappi-Tchamen Borel, Nana-Ndjangwo Stella Mariette, Nchoutpouen Elysée, Makoudjou Idene, Ngangue-Siewe Idriss Nasser, Talipouo Abdou, Mayi Marie Paul Audrey, Awono-Ambene Parfait, Wondji Charles, Tchuinkam Timoléon and Antonio-Nkondjio Christophe. Aedes mosquito surveillance using ovitraps, sweep nets and Biogent traps in the city of Yaoundé, Cameroon Insects 2022; 13, 793.
Idriss Nasser Ngangue-Siewe, Paulette Ndjeunia-Mbiakop, Nelly Armanda Kala-Chouakeu, Roland Bamou, Abdou Talipouo, Landre Djamouko-Djonkam, John Vontas, Konstantinos Mavridis, Jeannette Tombi, Timoléon Tchuinkam, Jean Arthur Mbida-Mbida, Christophe Antonio-Nkondjio. Bendiocarb and Malathion Resistance in Two Major Malaria Vector Populations in Cameroon Is Associated with High Frequency of the G119S Mutation (Ace-1) and Overexpression of Detoxification Genes. Pathogens. 2022; 11(8): 824. PMCID: PMC9330212 Christophe Antonio-Nkondjio, P. Doumbe-Belisse, L. Djamouko-Djonkam, C. S. Ngadjeu, A. Talipouo, E. Kopya, R. Bamou, M. P. Audrey Mayi, N. Sonhafouo-Chiana, D. L. Nkahe, R. Tabue, D. Achu Fosah, Jude D. Bigoga, P. Awono-Ambene, Charles S. Wondji High efficacy of microbial larvicides for malaria vectors control in the city of Yaounde Cameroon following a cluster randomized trial. Sci Rep. 2021; 11: 17101. PMCID: PMC8385066 Abdou Talipouo, Konstantinos Mavridis, Elysée Nchoutpouen, Borel Djiappi-Tchamen, Emmanouil Alexandros Fotakis, Edmond Kopya, Roland Bamou, Sévilor Kekeunou, Parfait Awono-Ambene, Vasileia Balabanidou, Sofia Balaska, Charles Sinclair Wondji, John Vontas, Christophe Antonio-Nkondjio High insecticide resistance mediated by different mechanisms in Culex quinquefasciatus populations from the city of Yaoundé, Cameroon Sci Rep. 2021; 11: 7322. PMCID: PMC8017000
Roland Bamou, Edmond Kopya, Leslie Diane Nkahe, Benjamin D. Menze, Parfait Awono-Ambene, Timoléon Tchuinkam, Flobert Njiokou, Charles S. Wondji, Christophe Antonio-Nkondjio. Increased prevalence of insecticide resistance in Anopheles coluzzii populations in the city of Yaoundé, Cameroon and influence on pyrethroid-only treated bed net efficacy. Parasite 2021 28 :8. PMCID: PMC7852377 Antonio-Nkondjio C, Ndo C, Njiokou F, Bigoga JD, Awono-Ambene P, Etang J, Ekobo AS, Wondji CS. Review of malaria situation in Cameroon: technical viewpoint on challenges and prospects for disease elimination. Parasit Vectors. 2019 Oct 26;12(1):501. doi: 10.1186/s13071-019-3753-8. |
