DR ALINE GAELLE BOUOPDA

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Background

Dr Aline Gaelle BOUOPDA TUEDOM defended her Ph. D in Parasitology at the Faculty of Medicine and Pharmaceutical Sciences of the University of Douala in 2024. Her thesis was focused on the evaluation of the malaria parasitological and entomological indicators in two different eco-epidemiological settings of Cameroun with high long-lasting insecticide nets (LLINs) coverage, project funded by IRD.

Before her Ph.D, Aline Gaelle had obtained a Master’s degree in Parasitology and Ecology from the Faculty of Sciences of the University of Yaoundé I in 2015, where she had evaluated the epidemiological aspects of malaria- loiasis co-infection in Mfou health district, Centre. She also holds a Master’s degree in Tropical Infectiology, obtained in 2014 from the “École Doctorale Régionale d’Afrique Centrale” in Franceville, Gabon. This Master’s degree focused on analyzing the involvement of Th17, Th1, and Th2 cytokines in the immune response to Plasmodium falciparum in children with malaria in Franceville, Gabon.

Before joining CRID, she worked as Research Assistant at the Malaria research unit of Centre Pasteur of Cameroon under the REMA (Relapsing of Malaria in Africa) project funded by NIH, where she supervised several field and laboratory activities to assess the dynamic of transmission of Plasmodium vivax and Plasmodium ovale in Dschang.

Since 2022, Dr Aline Gaelle has been an entomological consultant for the Cameroon National Malaria Control Programme (NMCP), contributing to malaria entomological monitoring in several regions of Cameroon.

Research:

During her Ph.D, Dr Aline Gaelle BOUOPDA TUEDOM established the antimalarial drug resistance profile in Centre and Adamawa regions more than 15 years after the change of drug policy in Cameroon by genotyping of Pfcrt, Pfmdr1, Pfdhfr and Pfphs resistance molecular markers.

She assessed the entomological profile of malaria and insecticide susceptibility of main vectors (Anopheles gambiae sl and Anopheles funestus). She revealed the possible change in vector behaviour with the outdoor host-seeking of Anopheles gambiae sl and the early morning biting of Anopheles funestus, which High level Pyrethroids resistance in these vectors in Mfou and Tibati locations.

Aline Gaelle had a high expertise in experimental infections of mosquitoes with Plasmodium natural isolates by direct membrane (DMFA) and she has contributed to several research projects on the malaria transmission blocking activity of mosquito antibodies (Timal, Malares, IMPAS, etc)

In November 2025, Dr Aline Gaelle BOUOPDA TUEDOM joined the Centre for Research in Infectious Diseases (CRID) as Postdoctoral Researcher under the CANVeCT (Catalyzing the Adoption of a Novel Vector Control Toolbox) project funded by Unitaid. This project aims to evaluate the safety and protective efficacy of spatial emanators as indoor vector control strategy to reduce the malaria burden in Cameroon

Areas of interest:

Antimalaria drugs and insecticides resistance molecular markers.

Evaluation of malaria transmission blocking activities of antiboties vaccine candidates using Experimental infection of mosquitoes with Plasmodium. falciparum natural isolates by direct menbrane feeding assays (DMFA).

Research groups:

Member of Wondji Research Unit (WoRu)

Other relevant expertise; Professionnal memberships:

– Entomological consultant of the National Malaria Control program (NMCP) of Cameroon.

– Member of PAMCA (Pan-African Mosquito Control Association)

-Member of AMMnet (Applied Malaria Modelling Network)

– Member of ASCAMVECT (Cameroon mosquito control association)

Scientific Publications

– Bouopda-Tuedom AG, Kiam CB, Aabate L, Bayibeki AN, Ibrahima I, Nanssong-Vomo CT, et al. Mosquito vector composition and biting behavior of malaria vectors in forest versus humid savanna eco-epidemiological settings of Cameroon. Malar J. 2026 Apr 2. https://doi.org/10.1186/s12936-026-05861-9

– Kiam BC, Bouopda-Tuedom AG, Mbida Mbida JA, Ibrahima I, Nanssong-Vomo CT, Abate L, et al. Reduced bio efficacy of used LLINs against natural populations of Anopheles gambiae sensu lato in the centre and east regions of Cameroon. Parasites Vectors. 2026; 19:95. https://doi.org/10.1186/s13071-025-07156-5

– Nanssong-Vomo CT, Feufack-Donfack LB, Bouopda-Tuedom AG, et al. Genetic polymorphism of Plasmodium falciparum isolates based on the merozoite surface protein 1 and 2 (msp-1 and msp-2) genes as a molecular marker in Oveng and Mintom, South Cameroon. BMC Infect Dis. 2025 Nov 19 ;25:1613. https://doi.org/10.1186/s12879-025-11923-1

– Samuel J. White, Valery P. K. Tchuenkam, Mariama Mbouh , Claudia Gaither, Aline Gaelle Bouopda-Tuedom, Belinda Kiam, Zachary R. Popkin-Hall, Jacob M. Sadler et al. Epidemiology of Relapsing and Falciparum Malaria in the Highlands1 of Cameroon: An Integrated Community Survey of Human Infection2 and Vector Abundance. PLoS Negl Trop Dis. 2025; 19(10): e0013549.

– Bouopda-Tuedom AG, Abate L, Feufack-Donfack BL, Ngou CM, Bayibeki AN, Moukoko CEE, et al.Genetic polymorphism of msp2 in Plasmodium falciparum isolates among asymptomatic malaria infections from two ecological settings in Cameroon. Malar J. 2025 ;24(1) :253.

– Kiam BC, Bouopda-Tuedom AG, Mbida Mbida JA, Ibrahima I, White SJ, Tchuenkam PVK, et al.Diversity of anopheline species and malaria transmission dynamics in high-altitude areas of western Cameroon. Malar J. 2025 ;24(1):251.

– Ngou CM, Bayibéki AN, Abate L, Makinde OS, Feufack-Donfack LB, Sarah-Matio EM, Bouopda Tuedom AG et al. Influence of the sickle cell trait on Plasmodium falciparum infectivity from naturally infected gametocyte carriers. BMC Infect Dis. 2023;23(1):317.

– Sarah-Matio EM, Guillochon E, Nsango SE, Abate L, Ngou CM, Bouopda Tuedom AG, et al. Genetic Diversity of Plasmodium falciparum and Distribution of Antimalarial Drug Resistance Mutations in Symptomatic and Asymptomatic Infections. Antimicrob Agents Chemother. 2022 ;66(8):e00188-22.

– Bouopda Tuedom AG, Sarah-Matio EM, Moukoko CEE, Feufack-Donfack BL, Maffo CN, Bayibeki AN, et al. Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes. PLOS ONE. 2021 ;16(8):e0256343.

– Feufack-Donfack LB, Sarah-Matio EM, Abate LM, Bouopda Tuedom AG, Ngano Bayibéki A, MaffoNgou C, et al. Epidemiological and entomological studies of malaria transmission in Tibati, Adamawaregion of Cameroon 6 years following the introduction of long-lasting insecticide nets. Parasites & Vectors.2021 ;14(1):247.

– Oyegue-Liabagui SL, Bouopda-Tuedom AG, Kouna LC, Maghendji-Nzondo S, Nzoughe H, Tchitoula-Makaya N, et al. Pro- and anti-inflammatory cytokines in children with malaria in Franceville, Gabon. AmJ Clin Exp Immunol. 2017 ;6(2):9-20.

aline.bouopda@crid-cam.net / gaellealine@yahoo.fr

(+237) 695371342

LinkedIn: Aline Gaelle Bouopda

https://www.linkedin.com/in/aline-gaelle-bouopda-88a2a194/

Appointment/title/role

Posdoctoral Research Assistant

Department

Parasitology and Microbiology

Departmental Research area

CANVeCT Project

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DR ALINE GAELLE BOUOPDA

Background

Research:

aline.bouopda@crid-cam.net / gaellealine@yahoo.fr

(+237) 695371342

LinkedIn: Aline Gaelle Bouopda

Appointment/title/role

Department

Departmental Research area

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