This work was presented within the context of a research project in partial fulfilment of the award of a Master’s degree in Animal Biology and Physiology. The jury, made up of lecturers from the Department of Animal Biology and Physiology of the University of Yaoundé I, approved the scientific nature of the study.
The jury approved the scientific nature of the study presented by Christophe Keumeni
The results that emerge from Christophe Keumeni’s analyzes indicate that, these two species of mosquitoes are present in all the districts surveyed. He observed that, Aedes aegypti was predominant in five of the eight neighbourhood surveyed. It should be noted that, the evaluation of the insecticide resistance profile revealed that Aedes aegypti and Aedes albopictus are indeed resistant to all classes of insecticides tested; except for Aedes albopictus, that revealed sensitivity to bendiocarb. Experiments with Piperonyl Butoxide (PBO) as a synergist suggest the existence of metabolic resistance due to cytochrome P450 monooxygenases. Christophe Keumeni demonstrated the presence of three kdr mutations. These are the V410L mutation with moderate frequencies, the V1016I mutation which also revealed a moderate frequency and the F1534C mutation which revealed a high frequency. Convinced by the conclusions of his work, this young researcher recommends to public authorities the urgent need to establish control and surveillance programs for arbovirus vectors in Cameroon. According to him, such programs should consider actions favorable to the improvement of water supply systems, environmental sanitation, health education and the use of insecticides in the event of an epidemic emergency. It has become imperative to set up permanent monitoring and control tools in order to curb resistance in the event of ineffectiveness of these insecticides.
The aim of Christophe Keumeni’s research was to assess the current geographic distribution of Aedes aegypti and Aedes albopictus mosquitoes in the city of Douala, the economic capital and main business center of Cameroon. The study also aimed at highlighting the insecticides resistance profile in the city. Specifically, it was an investigation carried out to note the degree of abundance, to map out the geographical distribution of Aedes aegypti and Aedes albopictus; to assess their susceptibility to insecticide as well as evaluate the potential mechanisms involved in insecticide resistance.
