PUBLICATION: Substrate promiscuity of key resistance P450s confers clothianidin resistance while increasing chlorfenapyr potency in malaria vectors By Magellan Tchouakui and al
Novel insecticides were recently introduced in public health by the World Health Organisation (WHO) to counter pyrethroid resistance threats in African malaria vectors. To prolong their effectiveness, potential cross-resistance from promiscuous pyrethroid metabolic resistance mechanisms must be elucidated. In our new paper in Cell Reports, Tchouakui et al used recently detected P450 DNA-based markers of…