PUBLICATION: The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus By Leon M. J. Mugenzi & al

Insecticide-based vector control measures are extensively used in the fight against malaria. Unfortunately, insecticides are in danger of losing their potency due to the development of resistance in vector species populations. The worst-case scenario is when a single resistance mechanism confers resistance to many insecticide classes, thereby hindering resistance management. Therefore, applying appropriate insecticide-based interventions…

PUBLICATION: Substrate promiscuity of key resistance P450s confers clothianidin resistance while increasing chlorfenapyr potency in malaria vectors By Magellan Tchouakui and al

Novel insecticides were recently introduced in public health by the World Health Organisation (WHO) to counter pyrethroid resistance threats in African malaria vectors. To prolong their effectiveness, potential cross-resistance from promiscuous pyrethroid metabolic resistance mechanisms must be elucidated. In our new paper in Cell Reports, Tchouakui et al used recently detected P450 DNA-based markers of…

MASTER DISSERTATION: Ngong Amy Futela now holds a master’s degree

On wednesday, July 24,2024 miss Ngong Amy Futela defended with distinction her master dissertation at University of Buea, department of biochemistry and molecular biology. Her study was placed under the theme : “ Allelic variation in glutathione-s-transferase epsilon 4(GSTe4) in pyrethroid resistance in Anopheles gambiae in Mangoum and Nkolondom, Cameroon”. Malaria is a deadly disease…