Malaria: the CRID-PMI collaboration in good shape

The partnership between these two entities in the fight against malaria greatly contributes to improve public health in Cameroon and in Africa.   In Cameroon, as in most countries where it is has been operationalized, the President’s Malaria Initiative (PMI) works to increase prevention and treatment means in malaria. PMI has been carrying out this…

Bill and Melinda Gates Foundation project 2 : developing field-deployable RT-PCR for vector surveillance

In malaria vector control surveillance, data concerning many important indicators can only be collected via laboratory-based molecular tests (i.e., species confirmation of species complexes, molecular mechanisms of resistance, Plasmodium infectivity). At present, transporting mosquitoes to laboratories for testing is a major rate-limiting step that can lead to months-long delays in receiving data, especially if there…

Bill and Melinda Gates Foundation project 1 : molecular markers for metabolic resistance to insecticides

In the major malaria vectors including An. funestus and An. gambiae metabolic mechanisms are driving resistance to most insecticides, including pyrethroids. But, contrary to target-site resistance such as knockdown resistance (kdr) for which DNA-based markers have been detected for more than two decades, until of recent, no DNA-based molecular assays were available to easily track…