PUBLICATION: “Two highly-selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b genes drive pyrethroid resistance in Anopheles funestus in West Africa”, by Nelly Manuela Tchatchoua & al
This study combines computational analysis and functional genomics experiments to provide in-depth insights into the molecular mechanisms by which the duplicated CYP6P4a and CYP6P4b genes are driving pyrethroid resistance in Anopheles funestus. Genotype-phenotype association studies were also used to assess the impact of these genes on the effectiveness of current vector control tools. Two key…