PUBLICATION: “Two highly-selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b genes drive pyrethroid resistance in Anopheles funestus in West Africa”, by Nelly Manuela Tchatchoua & al
Illustration caption: Fig. 3 In vitro assessment of pyrethroid metabolism by CYP6P4a and CYP6P4b candidate alleles. A CYP6P4a recombinant enzyme metabolism of pyrethroids. B CYP6P4b recombinant enzyme metabolism of pyrethroids. Values are mean ± SEM of three experimental replicates compared with negative control without NADPH. Depletion by recombinant resistant enzymes is significantly different from depletion…