Wellcome Trust: Can gene drive for malaria control be safely and sustainably implemented in Africa?

Despite significant progress in malaria control through improved treatment and vector control measures since the 2000s, recent years have witnessed a concerning stall due to the increasing prevalence of drug and insecticide resistance. To overcome these critical challenges, this Wellcome Trust-funded project (2022-2026) unites leading research institutions across Africa and the UK to investigate the…

Wellcome Trust: Characterising insecticide resistance-associated fitness cost and their compensatory genetic modifiers in major African malaria vectors

Malaria remains a devastating disease in the World (nearly 1/2 of the world population at risk) and particularly in Africa where more than 95% of cases are occurring. Prevention still primarily relies on vector control using insecticide-based interventions including impregnated nets which have significantly reduced malaria’s burden in Africa since their introduction. Given this heavy…