Background
I am a Senior Lecturer in Bayero University Kano, Nigeria. I received a PhD in 2015 from the Liverpool School of Tropical Medicine, supervised by Prof. Charles Wondji. My thesis addressed the role and allelic variation of resistance genes, the cytochrome P450s from the major malaria vector An. funestus on insecticides resistance across Africa. I was a beneficiary of the Wellcome Trust International Training Fellowship, through CRID, between 2017-2019, for a project entitled Accelerating malaria elimination efforts in Sudano-Sahelian region of Africa: elucidation of factors driving transmission and unravelling the molecular basis of insecticide resistance in the major malaria vectors. Since then I have been a member of Post-Graduate Research Initiatives Committee in the Centre for Research in Infectious Diseases, CRID, Cameroon, supporting research students research students and staff.
Research:
- Areas of interest:
Disease vectors, malaria, agricultural pests, pesticides, Plasmodium, antimalarials, genes, resistance, functional genomics, transcriptomics, modelling.
- Research – an overview of her research areas(s)
1. Using genome-wide transcriptional analyses, functional genomics and protein biochemistry to elucidate the molecular basis of insecticide resistance in mosquito vectors.
2. Molecular basis of pesticides resistance in agricultural pests, e.g. Tuta absoluta (tomato leaf miner), Tribolium castaneum (red flour beetle) and Spodoftera frugiperda (fall armyworm).
3. Investigation polymorphisms associated with antimalarial resistance in the major resistance genes kelch 13, pfmdr1 and pfcrt in Plasmodium falciparum isolates.
- Research Areas:
Molecular basis of insecticides, pesticides, and antimalarial resistance.
- PhD Students:
- Amen N. Fadel
- Maryam Maigari (BUK, Nigeria)
Other relevant expertise:
- Member Entomological Society of America (https://www.entsoc.org/)
- Associate Member Nigeria Infectious Diseases Society (https://nids.org.ng/)
- Member Pan-African Malaria Control Association (PAMCA) (https://pamca.org/)
- Member Nigerian Society of Biochemistry and Molecular Biology
Publications
1. Polymorphism Analysis of pfmdr1 and pfcrt from Plasmodium falciparum Isolates in Northwestern Nigeria Revealed the Major Markers Associated with Antimalarial Resistance Adam, Ruqayya, Mukhtar, Muhammad M., Abubakar, Umar F., Damudi, Hajara A., Muhammad, Abdullahi and Ibrahim, SulaimanSadi (2021) ‘Polymorphism Analysis of pfmdr1 and pfcrt from Plasmodium falciparum Isolates in Northwestern Nigeria Revealed the Major Markers Associated with Antimalarial Resistance’. Diseases, Vol 9, Issue 1, p. 6.
2. Exploring the Mechanisms of Multiple Insecticide Resistance in a Highly Plasmodium-Infected Malaria Vector Anopheles Funestus Sensu Stricto from Sahel of Northern Nigeria Ibrahim, SulaimanSadi, Mukhtar, Muhammad M., Irving, Helen, Riveron, Jacob ORCID: https://orcid.org/0000-0002-5395-767X , Fadel, Amen, Tchapga, Williams, Hearn, Jack, Muhammad, Abdullahi, Sarkinfada, Faruk and Wondji, Charles ORCID: https://orcid.org/0000-0003-0791-3673 (2020) ‘Exploring the Mechanisms of Multiple Insecticide Resistance in a Highly Plasmodium-Infected Malaria Vector Anopheles Funestus Sensu Stricto from Sahel of Northern Nigeria’. Genes, Vol 11, Issue 4, e454.
3. Identification of Mutations in Antimalarial Resistance Gene Kelch13 from Plasmodium falciparum Isolates in Kano, Nigeria. Umar F. Abubakar, Ruqayya Adam, Muhammad M. Mukhtar, Abdullahi Muhammad, Adamu A. Yahuza and Sulaiman S. Ibrahim. Tropical Medicine and Infectious Diseases, MDPI, 2020, 5 (2), 85; https://doi.org/10.3390/tropicalmed5020085
4. High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic.Ibrahim, SulaimanSadi, Fadel, Amen N, Tchouakui, Magellan, Terence, Ebai, Wondji, Murielle, Tchoupo, Micareme, Kérah-Hinzoumbé, Clement, Wanji, Samuel and Wondji, Charles ORCID: https://orcid.org/0000-0003-0791-3673 (2019) ‘High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic.’. Infectious Diseases of Poverty, Vol 8, Issue 1, p. 100.
5. High Plasmodium infection and multiple insecticide resistance in a major malaria vector Anopheles coluzzii from Sahel of Niger Republic.Ibrahim, SulaimanSadi, Mukhtar, Muhammad M, Irving, Helen, Labbo, Rabiou, Kusimo, Michael O, Mahamadou, Izamné and Wondji, Charles ORCID: https://orcid.org/0000-0003-0791-3673 (2019) ‘High Plasmodium infection and multiple insecticide resistance in a major malaria vector Anopheles coluzzii from Sahel of Niger Republic.’. Malaria Journal, Vol 18, Issue 1, p. 181.
6. A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of CameroonFadel, Amen, Ibrahim, SulaimanSadi, Tchouakui,, Magellan, Terence, Ebai, Wondji, Murielle, Tchoupo, Micareme, Wanji, Samuel and Wondji, Charles ORCID: https://orcid.org/0000-0003-0791-3673 (2019) ‘A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of Cameroon’. Parasites & Vectors, Vol 12, e263.
