Background
Marcel’s PhD research at the University of Montpellier in France focused on evaluating the effect of α-AnAPN1 antibodies (transmission-blocking vaccine) against field isolates of P. falciparum in Cameroon. To further his expertise in vector biology, he undertook a Postdoctoral fellowship at the Centre Pasteur du Cameroon where he worked on «Time-course of malaria gametocytes under transmission- blocking vaccines». In 2018, Marcel joined the department of medical entomology at the Centre for Research in Infectious Diseases (CRID) as a Postdoctoral and focused on investigating the correlation between the molecular basis of resistance and genetic structure of Anopheles funestus. Since 2019, Marcel has been appointed as a Research fellow at CRID where his group works on the interactions between Anopheles mosquitoes, their microbiome and the Plasmodium they transmit under PIIVeC (Partnership for Increasing the Impact of Vector Control) project funded by the UK GCRF through the Medical Research Council (MR/P027873/1).
Research:
| Entomology, Parasitology, Microbiology, Population genetic, Genomics and Bioinformatics |
Awarded grant1. Investigations of wAnD and wAnM Wolbachia strains in Anopheles moucheti and An. demeilloni in Cameroon, a collaborative project with LSTM funded by BMGF during 1st January 2023 to 31st December 2024. 2. Genetic diversity and maternal transmission of Microsporidia MB strains in field populations of the major malaria vector Anopheles gambiae s.l. in Cameroon funded by ANTIVeC during 1 st January 2022 to 31 December 2022 3. Impact of vector symbionts on malaria control and transmission in Cameroon funded by Research Councils UK Global Challenges Research Fund (GCRF) through Partnership for Increasing the Impact of Vector Control (PIIVeC) during 2019-2021
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- Areas of interest:
Interactions between Anopheles mosquitoes, their microbiome and the Plasmodium - Research – an overview of your research areas(s)
– Evaluating genetics approaches to render mosquito’s incapable of transmitting pathogens to humans |
- Other Relevent Expertise, PROFESSIONAL MEMBERSHIPS
1. Member of Application of Novel Transgenic technology & Inherited symbionts to Vector Control (ANTIVeC) 2. Member of Pan-African Mosquito Association (PAMCA)
3. Member of Gnatwork
- PhD students
Marcel is driven by a passion for mentoring and training the next generation of scientists, as well as closing the gaps in research capacity. Actually, he supervises 2 students with the names below: 1. MAFFO TATSINKOU Grace Claudine, Ph.D. Student
2. MBIATCHOUA POSSI Ornella Ingrid, Master Student
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Publications
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1. Fleuriane Metissa Djondji Kamga , Leon M J Mugenzi , Magellan Tchouakui , Maurice Marcel Sandeu , Claudine Grace Tatsinkou Maffo , Maximilienne Ascension Nyegue , Charles S Wondji (2023). Contrasting Patterns of Asaia Association with Pyrethroid Resistance Escalation between the Malaria Vectors Anopheles funestus and Anopheles gambiae. Microorganisms. 2023 Mar 2;11(3):644. doi :10.3390/microorganisms11030644. 2. Pierre Fongho Suh , Emmanuel Elanga-Ndille , Magellan Tchouakui , Maurice Marcel Sandeu , Darus Tagne , Charles Wondji , Cyrille Ndo (2023). Impact of insecticide resistance on malaria vector competence: a literature review. Malar Journal. 2023 Jan 17;22(1):19. doi: 10.1186/s12936-023-04444-2.
3. Maurice Marcel Sandeu, Claudine Grâce Maffo Tatsinkou, Nsa Dada, Flobert Njiokou, Grant L. Hughes and Charles S. Wondj (2022). Seasonal variation of microbiota composition in Anopheles gambiae and Anopheles coluzzii in two different eco-geographical localities in Cameroon. Medical and veterinary entomology. doi: 10.1111/mve.12583
4. Claudine Grâce Maffo Tatsinkou, Maurice Marcel Sandeu, Amen Nakebang Fadel, Magellan Tchouakui, Daniel Nguiffo Nguete, Benjamin Menze, Michael O. Kusimo, Flobert Njiokou, Grant L. Hughes and Charles S. Wondji (2021). Molecular detection and maternal transmission of a bacterial symbiont Asaia species in the field-caught Anopheles mosquitoes from Cameroon. (Parasites & Vectors)
5. Maurice M. Sandeu, Charles Mulamba, Gareth D. Weedall, Charles S. Wondji (2020). A differential expression of pyrethroid resistance genes in the malaria vector Anopheles funestus across Uganda is associated with patterns of gene flow. PLoS One 15(11): e0240743
6. Maurice M. Sandeu, Albert N. Bayibéki, Majoline T. Tchioffo, Luc Abate, Geoffrey Gimonneau, Parfait H. Awono-Ambéné, Sandrine E. Nsango, Diadier Diallo, Antoine Berry, Gaétan Texier and Isabelle Morlais (2017). Do the venous blood samples replicate malaria parasite densities found in capillary blood? A field study performed in naturally infected asymptomatic children in Cameroon. Malaria Journal. 16(1) :345.
7. Sandeu, M. M., Abate L., Tchioffo, M. T., Bayibéki, A. N., Awono-Ambéné, P. H., Nsango, S. E., & Morlais, I. (2016). Impact of exposure to mosquito transmission-blocking antibodies on Plasmodium falciparum population genetic structure. Infection, Genetics and Evolution, 45, 138-144.
8. Sandeu, M. M., Moussiliou, A., Moiroux, N., Padonou, G. G., Massougbodji, A., Corbel, V., & Ndam, N. T. (2012). Optimized pan-species and speciation duplex real-time PCR assays for Plasmodium parasites detection in malaria vectors. PLoS One, 7(12), e52719.
1. Travel Award to attend the 3rd Annual ANTI-VeC meeting at Kilifi in Kenya on 26-28 February 2023. 2. Travel Award to attend the 2nd International Conference on Public Health in Africa at Kigali in Rwanda on 13-15 December 2022.
3. Travel Award to attend the the 2nd Annual ANTI-VeC meeting at Imperial College in London on 20th – 21st June 2019.
4. Travel Award to attend the Conference on ‘Innovative Strategies for Vector Control’, in Wageningen (Netherlands) from Tuesday 11 to Thursday 13 June 2019.
5. Travel Award to attend the Keystone Symposium at the Hilton Addis Ababa, Ethiopia on Oct 30 – Nov 2, 2019, on The Malaria Endgame: Innovation in Therapeutics, Vector Control, and Public Health Tools.
