COMAL (Co-Infection Plasmodium Malariae)

COMAL (Co-Infection Plasmodium Malariae) This project aims to fully characterize the P. malariae parasites which is the least studied of the Plasmodium parasites and often reported as a benign malaria parasite due to the lack of data on this parasite. To fill this gap, Comal plans to determine the survival strategy of P. malariae through…

Impact of metabolic resistance to pyrethroids on the vectorial competence of the major African malaria vector Anopheles funestus

Mosquitoes that transmit malaria are becoming increasingly resistant to insecticides used to kill them. However, we still do not know if in addition to the ability to withstand insecticide exposures, resistance mechanisms also influence the capacity of mosquitoes to allow malaria parasites to develop in them, preventing to fully assess the damages that such resistance…

Investigating impact of insecticide resistance and immune system on Plasmodium falciparum development in the major malaria vector Anopheles funestus in Cameroon

About 90% of all malaria deaths in the world occur in sub Saharan Africa where resistance to antimalarial drugs and to most classes of insecticides are major obstacles for disease control. In the absence of an effective vaccine, novel control strategies are therefore needed. Among the novel approaches being investigated is the replacement of mosquitoes…